7 Best Supplement Stacks For Building Muscle in 2022

(Last Updated On: September 29, 2022)

jacked guy

Looking to build muscle, huh?

Of course, you are, or you wouldn’t be reading this.

Supplements can help a lot when it comes to building muscle and building it faster than you usually would.

The thing is…

Not all supplements are the same, and it can be hard to figure out which ones are total crap and which ones are worth your while.

Luckily we spent over 50 hours researching every supplement stack under the sun so you don’t have to.

Today, we will give you the best supplements stacks that build muscle that are on the market today.


Quick List: Best Muscle Building Supplement Stacks


Best Supplement Stacks for Building Muscle

Here are the 5 best supplement stacks on the market that can help you build muscle.


#1 The Bulk Muscle Building Essentials Stack

best muscle building supplement stack

Topping off our list of the best muscle-building stacks we have the Bulk Muscle Building Essentials Stack by Transparent Labs.

This stack is loaded with high-quality muscle-building supplements that will surely have you packing on muscle and strength fast.

This stack comes with 4 different supplements, all of which work with each other to add muscle. It includes their pre-workout designed for bulking, creatine HMB, Growth and 100% grass-fed protein powder.

Let’s take a look at each one of these bad boys individually and see what they bring to the table:


PreSeries Bulk

This is their pre-workout supplement that is designed for people who are looking to add serious muscle and bulk up. This monster contains 20 active ingredients designed to give you increased energy, muscle building, muscle pumps and laser focus in the gym.

This pre-workout is loaded with ample doses of citrulline malate for muscle and strength building, beta-alanine for delayed fatigue, and betaine anhydrous for increased strength and focus. It is also loaded with muscle-building BCAA‘s along with many other solid ingredients that deliver.


Creatine HMB

Next, in the stack, we have Creatine HMB. Creatine is already our favorite muscle-building supplement and when you combine it with HMB it makes it even better.

They also use Creapure in this supplement which is a German-made form of creatine monohydrate that is the best you can get. 5 Grams of Creapure creatine combined with 2 grams of HMB will increase your muscle and strength gains fast. On top of that, they use 5mg of Bioperine for better absorption and bioavailability. This one is really top-notch.


ProteinSeries 100% Grass-Fed Whey Protein

Next, we have a seriously high-grade form of protein here with 100% grass-fed whey. As you may know, protein is the building blocks of muscle This whey protein is from naturally fed, hormone-free cows, and it also has one of the industry’s highest protein-by-weight ratios at 88% making this some of the purest muscle-building protein out there.

On top of all that it has no artificial sweeteners, food dyes, gluten, or preservatives. This is some seriously high-quality stuff.



This is their advanced anabolic catalyst made to increase strength and amplify muscle growth, if you couldn’t tell that from the name.

The formula is simple, it’s only 1 ingredient, Mediator® Phosphatidic Acid. You are probably wondering what the Mediator Phosphatidic Acid is…

It’s a patented and studied ingredient that is proven to increase strength and muscle. Don’t just take my word for it though. In this study of sixteen resistance-trained men were randomly assigned to take Phosphatidic Acid or a placebo for 8-weeks. Men who took the Phosphatidic Acid had a greater increase in both strength and increase in lean body mass vs the placebo.

This study also found that “PA (Phosphatidic Acid) significantly activates mTOR and significantly improved responses in skeletal muscle hypertrophy, lean body mass, and maximal strength to resistance exercise”

Bottom line…

It’s another nice supplement in what is an already awesome muscle-building stack.


  • Coupon code TL10 saves you 10% on your order
  • Uses PreSeries Bulk – The premier muscle-building and bulking pre-workout on the market that is loaded with 20 active ingredients
  • Uses Creatine HMB – 5 grams of high-grade creatine monohydrate along with 2 grams of HMB
  • High-quality whey protein that comes from grass-fed, hormone-free cows and has one of the highest purity ratings on the market
  • Free shipping
  • Price saves $18 off of what you would pay buying the supplements separately


  • Only available on the manufacturer’s website
  • Above average in price


Overall this Bulk Muscle Building Essentials Stack is a serious heavy-hitter when it comes to muscle building. Their pre-workout is loaded with 20 ingredients designed to build muscle and give you a superior workout experience. The superior quality creatine and HMB is a surefire combo to add strength and muscle. Growth uses Phosphatidic Acid which is another proven muscle builder. On top of that, the high-quality protein powder will give you the building blocks to pack on even more muscle.

What’s the bottom line?

In our opinion, the Muscle Building Essentials Stack is the best muscle-building supplement stack on the market, bar none.

Shop www.transparentlabs.com


#2 Ultimate Fitness Stack

ultimate fitness supplement stack

Topping off our list, we have the Ultimate Fitness Stack from Crazy Nutrition as the best supplement stack for muscle gain.

This bad boy has everything you need to build muscle and get into fantastic shape. This stack might only be 3 supplements, but it is everything you need to pack on muscle. Let’s see what’s in this stack.



This is their creatine supplement, we love creatine and it is our favorite proven muscle-building supplement. This creatine uses a blend of 5 types of creatine and electrolytes to keep you hydrated.

CRN-5 uses a generous 6-gram dose of creatine that is primarily of creatine monohydrate (3.75 grams) and creatine HCL, ethyl ester, malate, and pyruvate.

We felt that the taste of CRN-5 is above average, but they do use artificial sweeteners. It also comes in only one flavor, Orange Mango.


Tri Protein

This is their protein supplement; it is also a blend of 6 different protein powders. This gives you fast, medium, and slow-release proteins to quickly feed your muscles after a workout with the quick-release protein while the slow-release protein feeds them all night long.

We went with the vanilla flavor, which is always a safe bet, it was solid, but it does use artificial flavoring.


Intensive Pre-Train

Their pre-workout supplement is made to deliver energy, focus, and, of course, muscle building. This bad boy is loaded with 19 ingredients that deliver. They use a massive 7-gram dose of citrulline malate, which builds muscles and provides serious muscle pumps. On top of that, they use betaine anhydrous, beta-alanine,l-tyrosine, l-theanine, taurine, ashwagandha, and more.

You can get this pre-workout with or without caffeine. We use the version without caffeine which is available in the Sour Apple flavor. It mixed up well and tasted great, but it used artificial flavors that some of you might not like.



  • Less expensive
  • Uses a generous dose of creatine
  • Protein is a mix of slow and fast release
  • Shipping is free
  • Buying the stack is $10 cheaper than buying the supplements individually


  • Only 3 supplements
  • Uses artificial flavoring and sweeteners



Overall this is a nice stack that delivers muscle-building ingredients like creatine, protein, and citrulline malate. It is only three supplements but they picked the three you would want in a muscle-building stack. I wouldn’t mind if they had thrown in some BCAAs, but I’m not complaining, it’s still a great stack.

It’s also the cheapest stack on this list. If you don’t mind artificial flavoring and sweeteners, you will love it.

Shop CrazyNutrition.com


#3 Build Stack by Swolverine

best muscle building supplement stack

The Build Stack by Swolverine is legit. This bad boy features 5 supplements stacked together that will have you building muscle faster than you have ever imagined.

This stack includes Kre-Alkalyn, Citrulline Malate, Beta-Alanine, Whey Protein Isolate, and L-Glutamine.

Here is the breakdown on each:



This is their creatine supplement. It is pH stabilized, so it doesn’t go into solution and cause bloating like regular creatine monohydrate can. It also helps to increase strength and power output while building muscle.

While traditional creatine monohydrate has a 5-gram dose, you only need 3 grams with Kre-Alkalyn, which is exactly the dose on this supplement. We also really like that each tub has 100 servings.


Citrulline Malate

This non-essential amino acid helps increase energy production and delays muscle fatigue, helping you push harder in your workouts. It is commonly used in pre-workout supplements. They made it a stand-alone supplement for this stack. The 5000mg dosing is solid.


Beta Alanine

This non-essential amino acid helps increase muscular endurance, allowing you to push through your workouts and have more reps. This supplement has a generous 5000mg dose which is more than enough to do the job.


Whey Protein Isolate

This fast-absorbing protein is perfect for post-workout when your muscles need protein the most. It also helps with the recovery and repair of muscle tissue. Whey protein isolate is a better form of whey protein than the traditional concentrate. You are getting the good stuff with this stack.

Each scoop has 26 grams of protein which is above average.



This is a conditionally essential amino acid that helps with recovery and muscle growth. It also helps reduce stress levels and improve mental focus, which is always a good thing when working out.

The 5-gram dose is solid, this stuff is pretty cheap, so they could have put in a smaller amount, but they didn’t, which is always a good sign.

This stack has everything you could ever want or need in a muscle-building supplement stack. It’s complete and has generous dosages of everything. It’s also reasonably priced, especially considering all that you are getting.

You can’t go wrong with this one.


  • 5 Supplements in 1 stack
  • High-quality whey protein isolate
  • All supplements use generous dosing
  • The stack is $20 less than the supplements would be if they were bought individually
  • One of the best stacks for muscle gain


  • Expensive (You do get 5 supplements, which is more than you get with the others on the list)
  • Not always in stock

Shop Swolverine.com


Related: Best Pre-Workout Supplement for Building Muscle Mass


#4 The Beast Stack by Beast Sports

The Beast Stack from Beast Sports Nutrition is up next. This one is another nice stack that will build strength and muscle along with your testosterone levels and libido which is a bit unique from the other stacks on the list.

It is also made in the USA by a reputable company in a gCMP facility so you know it is high quality. Let’s take a look at what you get in this stack.


Creature Creatine

The stack starts off with one of the best creatine supplements on the market with Creature. This creatine supplement is a blend of 5 creatines made to increase muscle and strength and also speed recovery.

Creature offers some of the best flavors out there but they do use artificial flavoring, they also offer in unflavored for those who want to avoid anything artificial.


Super Test

Super Test is the testosterone-boosting supplement put out by Beast Sports. Super Test is made to increase your testosterone levels which makes it easier to build muscle, reduce body fat and it also helps with the libido.


Beast Mode Black

Beast Mode Black is their pre-workout supplement. While the name is intimidating it is missing a couple of key ingredients like citrulline malate and beating anhydrous. Beast Mode Black also boasts a massive 400 mg dose of caffeine which some people might really like but it may be too much caffeine for others.



  • Less Expensive
  • Features high-quality creatine
  • Increases testosterone levels and boosts libido
  • Pre-workout provides a massive energy boost


  • Only uses 3 products
  • Uses artificial flavors
  • Pre-workout is missing key ingredients and may have too much caffeine for some people



Overall the Beast Stack is another nice muscle-building stack that is less expensive. It is not as high quality as our top selection but if you are looking for something lighter on your wallet this stack is one to consider. It features a really nice creatine and a quality testosterone booster. The pre-workout is middle of the road but will give a nice energy boost with a 400 mg caffeine dose. We would like if they included a BCAA as well but overall this is still a pretty solid selection.

Shop BeastSports.com


#6 Ultimate Muscle Buiding Stack by Jym

best supplement stacks

Next up we have another nice muscle-building stack by Jym Supplement Science.

This bad boy features 4 supplements as well as a nutritional ebook that will hook you up with all of the best muscle-building foods and recipes.

Let’s take a look at what supplements this stack has to offer…

Pre Jym

Pre Jym is their top-of-the-line pre-workout that comes with muscle-building ingredients like creatine, beta-alanine, betaine, and BCAAs. It also delivers the focus and alertness that you would expect from a pre-workout supplement.

This supplement comes in 8 delicious flavors for you to choose from. On the negative side, they do use artificial flavoring.


Pro Jym

As you may know, protein is the building block of muscle so more protein will help you build muscle. This is their protein supplement that delivers a blend of whey, casein, and egg proteins to provide slow, fast and medium digesting proteins.

On the negative side, this one also contains artificial flavoring.


Post JYM BCAA+ Recovery Matrix

This is their post-workout supplement, it is loaded with 6 grams of BCAAs, 2 grams of creatine HCL, 2 grams beta-alanine, 1.5 grams of betaine and 2 grams Carnipure® L-carnitine L-tartrate. When it comes to post-workout supplements, this is one of the best ones out there.


Omega JYM

This is their fish oil supplement. Fish oil is loaded with Omega 3 Fatty Acids which have been shown to be beneficial for your heart and brain and can also help you burn fat and build muscle.


  • Includes nutritional ebook
  • Pre-workout supplement is solid
  • Manufacturer has a solid reputation


  • Expensive
  • Uses artificial flavoring



Overall this is another nice selection for those that are looking to build muscle. I would avoid it if you do not like artificial flavoring but other than that, it is another one of those solid supplement stacks for lean muscle mass.

Shop JymSupplementScience.com


#6 Build 24/7 Stack by Jacked Factory

supplement stack

This stack is definitely for you if you are on a tight budget and want to boost muscle growth. 

This stack isn’t as good as the stacks at the top of the list, but it’s only a fraction of the price.

This stack is made in the USA and is free of dyes and fillers, and is also vegan friendly. 

Let’s take a look at what’s inside this bad boy:

Growth Surge

This is their post-workout supplement. As you can tell by the name, it is made to promote muscle growth.

They use a pretty simple formula, just four ingredients overall. The ingredients include creatine, betaine anhydrous, l-carnitine l-tartrate and Bioperine for absorption. This is a solid supplement, but it uses artificial sweeteners, which is a negative for some.

Build XT

The latest edition of Build XT is here to help you become a more advanced athlete. With cutting-edge ingredients like PeakO2, ElevATP, and Astragin for muscle growth, strength, and endurance, this product will have your body ready in no time.

Build PM

Build PM is their nighttime muscle builder. This is important because sleep is essential for muscle building.

Build PM uses melatonin to promote sleep and ashwagandha to reduce stress and boost testosterone levels. Then they also use l-theanine to promote restfulness and improve mood and tart cherry to promote strength and recovery.

Overall this is a pretty good stack for the money. It’s only 3 supplements, but they are all pretty decent. We lake the Growth Surge the most of the 3.

Another nice thing is you save a bundle by buying these three supplements in a stack rather than individually. This stack is $37 less than it would be if you purchased each supplement individually; that is serious savings right there. It almost feels like they made a mistake and forgot to raise the price of the stack when they raised the supplement prices. I won’t tell.


  • Budget-friendly
  • Solid post-workout supplement
  • Promotes sleep


  • Uses artificial sweeteners
  • Only three supplements

Shop JackedFactory.com


#7 The Build Muscle Stack

Muscle building supplement stack

This stack is also pretty good so we thought we would as it as a bonus. It’s the Build Muscle Stack from Legion Athletics, this one is a good stack of 4 supplements that are designed to build muscle if you couldn’t already figure that out by the name of the stack.

Legion Athletics has become one of the top names in the supplement industry so it isn’t much of a surprise to see that their stack is on here; let’s take a look at what is included in this stack.


Pulse Pre-Workout

First up, they have their pre-workout supplement, this one is designed to give you a serious energy boost and improve focus. This one has a really nice dose of Citrulline DL-Malate as well as betaine anhydrous and beta-alanine for nice muscle building and endurance.

It doesn’t have near the twenty ingredients that the pre-workout in our first stack has but it does have some nice doses of the listed ingredients.



Next up they have a nice whey protein to help you get that quick protein shot after your workout to help your muscles grow.  They use whey protein that comes from hormone and antibiotic-free cows from dairy farms in Ireland.

This whey protein also doesn’t have any artificial flavors or dyes, GMOs, gluten or any other junk in it, just nice, clean protein.



This is their post-workout supplement to help you recover and grow those muscles. This supplement contains 5 grams of creatine monohydrate which we love along with L-carnitine L-tartrate and corosolic acid.

L-carnitine L-tartrate has been shown to aid in muscle recovery and may increase testosterone levels, both of which help with muscle growth.



Lastly, we have Triumph which is their multi-vitamin.

This multi-vitamin contains 35 ingredients designed to promoted health and well being and also plug holes in your diet. It can also boost energy and keep you sharp physically and mentally.


For this stack, they recommend you take the multi-vitamin with breakfast and dinner, Pulse pre-workout and whey protein before your workout and take the Recharge post-workout supplement and 1-2 scoops of the whey protein.



  • Use high-quality protein powder with nothing artificial
  • Post-workout uses creatine monohydrate and  L-carnitine L-tartrate
  • Pre-workout has ample dose of Citrulline DL-Malate
  • Less expensive


  • Only 6 active ingredients in the pre-workout
  • Multivitamin seems like a throw-in


This stack by Legion Athletics is another good choice for muscle building. We really like the post-workout and whey protein they use. The pre-workout could use some more muscle-building ingredients but we do like the 6 that they have in there. The multivitamin seems like a throw into us and likely won’t really do much in the way of building muscle, it’s good to take but not really going to do much for muscle building at all.

Shop legionathletics.com


Related: Top 10 Supplements for Muscle Growth


What is a Supplement Stack?

A supplement stack is simply a group of supplements that work together to build muscle. Sometimes it can be just two supplements stacked together, or some stacks also go up to 6 different supplements, it all depends.

While one supplement can help, grouping a few supplements together that work together for a common goal can be much more effective than just taking one supplement and hoping it can do it all.

Commonly a supplement company will offer supplement stacks of their products that are made to go together or work well together, and these stacks can be geared toward building muscle or burning fat. Today, we are covering the best supplement stack for muscle gain.

Girl with Muscle

What to Look For in A Supplement Stack


Avoid Steroid Alternative Stacks

If you search around enough, you will likely come across a website or two recommending you get a stack of steroid alternatives. These should be avoided.

It’s not because they are dangerous or anything like that. It’s because they are entirely ineffective. These “supplements” are usually just very small amounts of branched-chain amino acids they are selling and marketing as “having the anabolic effects of steroids”.

Truth be told, steroid alternative supplements are about as effective as a placebo. The only thing they are really good at is taking money out of your wallet. Anyone who recommends them is not credible and you should run the other direction unless you really enjoy being ripped off.


What to Look For in A Supplement Stack


When looking for a supplement stack for building lean muscle, you want to make sure that the products included have ingredients that actually help with building muscle. Some common muscle-building ingredients are creatine, beta-alanine, BCAAs, protein, and citrulline malate.

You also want to make sure that the doses of these ingredients are in line with what has been studied to be effective. If a product is under-dosed, it likely won’t work as well as it could, and if it’s over-dosed, you could even experience some side effects.


You also want to make sure that the products in the stack are designed to be taken at different times of the day. For example, a pre-workout supplement should be taken before your workout, and a post-workout supplement should be taken after your workout. If you take all the products in the stack at the same time, you likely won’t get the full benefit of each product.


Money doesn’t grow on trees, so of course, money is a consideration. But you don’t want to cheap out on a supplement stack because you could end up with underdosed and ineffective products.

At the same time, you also don’t want to overpay for a supplement stack that has a lot of flash but not a lot of substance, like those fake steroid stacks that do nothing but take your money. There are many great options out there that are priced very reasonably. All of the stacks on this list are a pretty good value.

What Supplements are in the Stack

When looking for a stack to promote lean muscle growth, you need to look at what supplements are in the stack. Some companies put supplements in their stacks that aren’t going to help you build muscle, like multivitamins and fish oil. Even pre-workouts aren’t really going to help you build muscle unless they are designed to.

Muscle-building supplements to look for in a stack include creatine, protein powder, branched-chain amino acids, post-workout supplements, and pre-workouts made to build muscle.


When trying to find the best supplement stack, reviews from other customers can be beneficial. You can learn a lot about a product from what other people have said about it, both good and bad.

Of course, you should take everything you read on the internet with a grain of salt, but if you see a lot of people saying good things about a certain product, it’s likely that the product is effective. And if you see many people saying bad things about a particular product, it’s likely that the product is ineffective.

When looking for reviews, try to find ones that are from unbiased sources, like blogs or forums. You don’t want to just read the reviews on the company’s website because they are obviously going to only put the good reviews on there.


Overall Conclusion

If you’re looking to bulk up, the right supplement stack can make all the difference. We’ve highlighted some of our favorite stacks for building muscle, but it’s important to do your research and find the supplements that work best for you. With a little hard work and the right supplementation, you’ll be on your way to achieving the body you’ve always wanted. Have you tried any of these supplement stacks? What was your experience? Let us know in the comments below!