5 Best Nitric Oxide Supplements For Muscle Pumps 2022

(Last Updated On: January 17, 2022)


Jacked guy on nitric oxide supplements

Nitric oxide supplements can be your best friend if you’re looking to bulk up and get maximum muscle gains when you go to the gym or get enhanced physical performance in any sport. More than that, nitric oxide helps to improve various aspects of a man’s life, most notably the ability to perform in the bedroom.

But simply getting the first nitric oxide supplement you see isn’t good enough. Like all products, there are some nitric oxide pills that are better than the others in terms of ingredients, dosage and manufacturing.

You may be astounded at the sheer number of available NO enhancers in the market, but don’t worry. We’ll provide a comprehensive guide to the best nitric oxide supplements available today!


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What Are Nitric Oxide Supplements?

Before we get to the supplement itself, it helps to gain an understanding of what Nitric Oxide really is and how you can benefit from taking it.

Nitric Oxide, or otherwise known as NO, is a byproduct that forms when nitric oxide synthases break up Arginine, an essential amino acid. Simply put, it’s a form of molecule that works deep within one’s vascular system, signaling the blood vessels to widen and allowing more blood, oxygen and other nutrients to get to where they need to go.

Numerous research and scientific studies have found that this particular gas contains remarkable properties, able to relax smooth muscles within blood cells to improve blood flow, cell communication and vasodilation.

Nitric Oxide supplements, therefore, are dietary pills or products that give you more nitric oxide to work with. You can take advantage of this increased NO compound when you’re working out at the gym or when you need that boost for a better performance.

The best NO supplements typically contain the following ingredients- Arginine, Citrulline, Beta Alanine and Glutathione, which will be covered in greater detail below. The two essential amino acids, Citrulline and Arginine are excellent nitric oxide precursors that really improve NO serum levels within the body.


Best Nitric Oxide Supplement Ingredients


Arginine, a.k.a L-Arginine is an important ingredient in any nitric oxide supplement. First, this amino acid helps with the production of HGH, or human growth hormones, which in turn torches the stubborn fat hidden deep within your muscles. When the fat cells are eliminated, the lean muscle will have more space and room to grow. HGH is beneficial to overall health as it improves energy levels, well-being and believe it or not, cognitive health.

The beauty of Arginine is that it’s one of the best and safest ingredients you can use to boost HGH production. An abundance of HGH can be converted into extra testosterone or whichever hormone you need at the moment. You get a significant decrease in rest periods after workouts and get back on bodybuilding the soonest possible time.

Various medical research shows that Arginine can also help facilitate weight loss, improve your tolerance to strenuous physical activities and lower blood pressure to optimal levels. More than that, L-Arginine helps relieve the embarrassing symptoms of erectile dysfunction as it has the ability to relax the corpus cavernosum muscles and achieve a more satisfactory erection.


The other amino acid in Nitric Oxide supplements, Citrulline does the same things as Arginine does, making it the perfect complement in terms of synergistic benefits. This means that Arginine won’t work as well without having Citrulline in the mix, and vice versa.

Citrulline, in effective doses, can increase the flow of blood, oxygen and important minerals straight to the muscle cells. Notable benefits of taking Citrulline include decreased muscle soreness and fatigue, increase physical exertion and stamina, lessen the effects of ED, improve heart function and allow the body to produce more HGH after exercise.

Beta Alanine

Beta Alanine is no stranger in the world of bodybuilding. This amino acid literally takes off the physical limiters that occur when you exercise too much. Ever wonder why your muscles can’t keep up and get fatigued when you start pumping iron without rest? The reason for this is simple- your muscles get tired due to the acid buildup while exercising for extended periods of time.

Beta Alanine dissipates the acid that builds up during strenuous physical activity, i.e., when you’re at the gym, pumping iron, in sports and while doing vigorous cardio exercises. Studies have found that Beta Alanine works wonders when you’re trying to delay the onset of fatigue when partaking in intensive exercise with little to no recovery periods.

Beta Alanine also plays a large role in increasing muscle mass. You get increased stamina and endurance via greater oxygen intake, resulting in a sculpted body without the fat.


Glutathione is comprised of 3 essential acids, namely cysteine, glycine and glutamine. It’s an antioxidant that’s naturally produced by the body and is an important element for your health and cellular integrity. Health experts cite Glutathione as the “Master Antioxidant” because it helps keep your liver and your immune system healthy and safe from free radical damage.

You may think of Glutathione as something that’s unimportant, but this is not the case. You’ll need a powerful antioxidant when you’re trying to achieve body and muscle perfection because these activities deplete Glutathione production. Without Glutathione, your body ages much faster and muscle building and recovery take a significant hit. This remarkable compound allows you to achieve peak physical and mental function, reduce muscle damage and recovery time, and best of all, plays a role in converting stored fat into lean muscle mass.


Benefits of Nitric Oxide Supplements

Massive Boost In Muscle Performance

Nitric Oxide supplements give you a welcome boost in terms of gaining more pump and gives you your best performance yet. When vasodilation or the process of widening blood vessels occur, all the blood in your body will move at a much faster pace, which means all the nutrients and oxygen will be delivered quickly and efficiently.

You start experiencing the “superhuman” effect, where you start feeling more power. You’ll have the capability to carry out impressive feats at the gym, the sports field or wherever you need it. More blood rushing to the muscles means you get greater strength. More oxygen means there will be less lactic acid buildup, which translates to greater stamina and endurance. Bodybuilders and athletes can easily smash through personal plateaus and go farther in terms of physical limits. More pump also equals a greater chance to develop more muscles.

Nitric oxide supplements to build muscle

Quicker Recovery Time

Thanks to L-Citrulline, NO supplement users can look forward to a much faster recovery time after a hypercharged workout session. The production of more nitric oxide leads to lesser muscle stress. This means that you can plan the next gym session much sooner if you take nitric oxide pills.

The remarkable ability of Citrulline malate increases blood flow while clearing waste products such as ammonia and lactic acid, the two worst offenders in muscle fatigue. As above, less time needed to recover means you can visit the gym at a sooner rate, which equals more chances to develop lean muscles and get the physique you’re dreaming of.


Treats Erectile Dysfunction

Erectile dysfunction is a condition where one fails to achieve a satisfactory erection for sexual purposes.

Individuals who are suffering from the effects of ED may find help in the form of Nitric Oxide supplements. Though most of these NO products are marketed towards bodybuilders, gym goers and athletes, there’s no stopping ED patients from trying it out to achieve sexual satisfaction.

As you may know, nitric oxide widens the blood vessels, allowing more blood to flow to the muscles and other extremities, including the penis. The mechanism of action allows the chambers found inside the penis to fill with blood and get rock hard results. Men who want to satisfy their partners can take the pill and get their manhood up for maximum performance in the bedroom.


The Best Nitric Oxide Boosters

These are the 5 best Nitric Oxide Boosters in the market today. Take a look at why they made the list, along with a list of the pros and cons:

1. NO XT by Jacked Factory


N.O. XT is an awesome nitric oxide booster. Manufacturer Jacked Factory ensures that all the important ingredients are in it, and added a few more for good measure. Nitric oxide delivery is spot-on with NO XT. What’s more, you get muscle fullness and a skin-tearing pump courtesy of the potent ingredients in each bottle.

Power output is impressive, as is stamina and endurance. The product is manufactured in a cGMP-certified facility for maximum potency and efficacy. NO XT’s ingredients include Glutathione, Nitrosigine, Citrulline and Bioperine. What’s more, there are literally zero side effects to speak of and the effects are powerful enough to last you the entire workout session.

You can’t go wrong with choosing N.O. XT by Jacked Factory, whether you’re a beginner who’s starting out or an experienced bodybuilder or athlete who wants to try out something better. You’ll be smashing plateaus and personal records in no time!


  • Contains important ingredients for maximum nitric oxide production.
  • Great value for money.
  • Long-lasting energy and stamina effects.
  • Provides an incredible pump.
  • Made by Jacked Factory, one of the best supplement manufacturers in the U.S.


  • Only available on the manufacturer’s website

Website: jackedfactory.com



2. Fermented Citrulline

Best Nitric Oxide Supplements

Next up we have Fermented Citrulline from Kaged Muscle.

This supplement is designed to do one thing, give you better muscle pumps in the gym.

It does this by using 2 grams of fermented L-Citrulline.

L–Citrulline is an amino acid that plays an important role in NO. In the body, l-citrulline is converted into L-Arginine, this leads to an increase in L-Arginine and nitric oxide. Long story short, this means serious muscle pumps for you.

This bad boy doesn’t use caffeine either so you don’t have to worry about crashing.

If you’re not 100% happy with the results after 30 days, you’ll get your money back!


  • No filler ingredients, just fermented L-Citrulline
  • Inexpensive
  • Not made from duck feathers or human hair like most L-Citrulline products
  • Vegetarian friendly


  • You can only buy from their website.

Website: KagedMuscle.com


Related: Supplement Stacks That Build the Most Muscle


3. BSN Nitrix 2.0

BSN Nitrix 2.0

Nitrix 2.0 is a concentrated supplement that offers a well-rounded support for your weight training and performance goals. The manufacturer claims you’re getting 3 grams of essential amino acid Citrulline, which promises greater pump, endurance and shorter recovery time.

Tablet count per day is still high at 6, but you get a vasodilator that works when you need it the most. As with other top-notch nitric oxide supplements, Nitrix 2.0 contains proven ingredients such as L-Citrulline, Niacin, Hawthorne Extract, Pomegranate, Grape Seed Extract, Red Pepper Extract, Black Pepper Extract and Pterostilbene.

Having too many ingredients can lead to a detrimental effect where it matters most- the pump. Nitrix 2.0, when compared to the top 3 in this list, has become somewhat diluted and provides fewer performance gains as a result.


  • Offers a better absorption rate of amino acids and essential nutrients.
  • Contains compounds that support metabolic functions.
  • Contains Creatine.
  • Provides a decent amount of energy.


  • Too many ingredients lower its potency.
  • Creatine and water retention could give you a non-ripped appearance.
  • Does not contain Arginine, one of the best ingredients in a nitric oxide booster.

See this product on Amazon


4. Cellucor NO3 Chrome

Best Nitric Oxide Supps

NO3 Chrome is advertised as a stimulant-free nitric oxide booster for greater pump performance. The product uses a proprietary blend called NO3 in the form of Arginine Nitrate, which is Nitrate and L-Arginine combined. The manufacturer claims that you get better, more awesome pumps that you can ever acquire from other NO booster brands. Other ingredients include Arginine Nitrate, Arginine AKG, L-Citrulline and Grapeseed Extract.

The pre-workout supplement works wonders in increasing pump and performance, but they fall short when put on a side-by-side comparison with the top 3 nitric oxide enhancers in this list. When you take a closer look at the ingredients, they’re not as potent as NO XT, NO2 Max or the best NO booster, NitroCut.


  • Citrulline Malate is one of the best forms of L-Citrulline.
  • All natural ingredients mean there’s less risk of side effects.
  • Can be used in a performance-enhancing stack.
  • Gives a reasonable amount of energy and stamina.


  • Too expensive to be used long term.
  • Dosage is quite high for it to take effect.
  • Secret proprietary formula means you’re likely getting lower dosages of the important ingredients.

See this product on Amazon


Related: The 10 Best Supplements to Make Your Veins Pop


5. NO2 Max by CrazyBulk

NO@ Max Supplement

CrazyBulk has a proven track record for churning out the best supplements, and they do it yet again with the NO2 Max.

The nitric oxide booster contains all-natural, potent ingredients that have been scientifically proven to work big time. When you get NO2 Max you’ll be putting yourself in a position to succeed, whether your goal is to get ripped, get massive gains or perform your best in sports and other athletic activities.

Users can combine NO2 Max with other performance-enhancing stacks to achieve an even greater gain. You can rely on this proven NO supplement to achieve your goals and continue on with getting the body you want. The insane recovery period ensures you can go back to the gym and do it all over again much faster than expected. Don’t be surprised when you start seeing massive results in as little as a month!


  • Get steroid-like effects without the actual steroids.
  • One of the best nitric oxide boosters that work very well.
  • Get an awesome pump and greater endurance.
  • NO2 Max can be stacked with other muscle-boosting supplements.


  • Growing muscle still requires hard work and dedication from you.



Try out our #1 recommendation NO by Jacked Factory, if you want to get the best possible results. The other 2 in the list are also top contenders with their own pros and cons. These are the best nitric oxide supplements you can get if you want to get ripped, bulked up and become the envy of your peers. Open up a whole new world of muscle-building and performance possibilities with these NO supplements today!