7 Best Nitric Oxide Supplements For Muscle Pumps 2025

 

This stuff isn’t hype, it’s the real deal when it comes to pushing more blood, more oxygen, and more nutrients into your muscles while you train. That means bigger lifts, better endurance, and freakier vascularity without having to live in the gym.

But not all NO supplements are created equal. Some are loaded with filler. Others don’t have enough of the right ingredients to actually do anything. That’s why we sorted through the trash and pulled together only the heavy hitters, the ones with science-backed doses, real-world results, and no fluff.

So if you’re ready to train harder, recover faster, and maybe even show up stronger in the bedroom… keep reading. This list is your shortcut to the best nitric oxide boosters on the market today.

 

The Best Nitric Oxide Boosters

These are the best Nitric Oxide Boosters in the market today. Take a look at why they made the list, along with a list of the pros and cons:

 

#1 Nitric Oxide by Transparent Labs

If you’re chasing a nitric oxide supplement that actually does something, something noticeable, you need to check out Nitric Oxide by Transparent Labs. This isn’t some overhyped powder stuffed with caffeine and flashy packaging. It’s clean. It’s direct. It works.

What’s inside matters. Arginine Nitrate, Betaine Nitrate, L-Glutathione, and Pine Bark. Each one plays a role in helping your blood flow better, so your muscles get what they need when it counts. More pump. Better recovery. Less time feeling like you got steamrolled the day after leg day.

And here’s the kicker, no stimulants. Zero. That means no jitters, no crash, no weird late-night regret if you train in the evenings. Plus, no artificial dyes, no junk. You’re getting 120 capsules, enough for 30 real-deal servings. That’s a full month of pushing harder and feeling it.

Transparent Labs has this thing where they actually tell you what’s in the bottle and why it’s there. No hiding behind “proprietary blend” garbage. Just straight-up ingredients, clear dosages, and a formula that’s backed by actual thought.

Yeah, it’s a little pricier than the average bottle you’d find in the bargain bin. But here’s the move, use the code TL10 and take 10% off. Set up a subscription? Boom. Another 10% off and free shipping on top.

So if you’re serious about training, about improving blood flow, about showing up and getting after it instead of just going through the motions, this one’s for you.

Pros

• Buying in bulk saves money
• Nothing artificial
• Gluten free and Non GMO
• Uses Arganine Nitrate, Betain Nitrate and L-Glutathione

Cons

• Above Average in Price
• Only available on the manufacturer’s website

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#2 Onnit Total Nitric Oxide

Alright, here’s the rundown on Onnit Total Nitric Oxide, and let’s just say, it’s a bit of a different beast.

Instead of capsules, you’re getting a powder. Some people love that. Others, not so much. But if you’re the type who’d rather drink your supplements than choke down pills, this might feel like a win. Just mix and sip. No grimace needed.

Now, the core of this thing is L-Citrulline DL Malate. Three full grams of it. That’s the heavy lifter here. It kicks off the nitric oxide production in your body, which means better blood flow, more endurance, and pumps that actually look like something’s happening.

But Onnit didn’t stop there. They tossed in fermented beet root and mango fruit powder, which might sound like a smoothie recipe, but it’s all in there to help crank nitric oxide levels even higher. No caffeine, no junk, just natural stuff that plays nice with a keto diet and won’t leave you wired at midnight staring at the ceiling.

Now here’s where it stumbles a little. You only get 20 servings per tub. So yeah, it’s a little steep on the cost per scoop. And if you’re looking to load up, there’s no “buy more, save more” deal. You do get a 15% discount if you subscribe, which helps, but shipping’s not free unless your cart hits $150.

Bottom line? If you’re looking to shake up your pre-workout game and don’t mind splurging a bit for a solid, natural formula that skips the stimulants, Onnit Total Nitric Oxide might be your move. It’s smooth, clean, and brings a different vibe to your supplement stack.

Just don’t expect it to be cheap. Great rarely is.

Pros

• Can help boost nitric oxide levels
• Contains L-Citrulline DL Malate
• Comes in powder form (which may be better for some)
• Naturally flavored

Cons

• Above average price
• Only 20 servings per container

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Related: How to Get Veiny Arms: Guide to Vascularity

 

#3 NO XT by Jacked Factory

Let’s talk about N.O. XT by Jacked Factory. This isn’t just another bottle on the shelf promising big pumps and then ghosting you in the gym. No, this one’s built different, and it shows.

From the jump, you can tell they didn’t just throw together whatever sounded cool on a label. The ingredients are there for a reason. Citrulline, Nitrosigine, Glutathione, Bioperine… it’s a stacked crew, and they actually work together. Not just to give you a quick pump and fade, but to carry you all the way through your session, from the first rep to that last slow, painful grinder.

And those pumps? They’re no joke. We’re talking the kind of muscle fullness that makes your shirt feel tighter by the set. You look in the mirror and think, yeah, I’m doing something right. And the best part? It’s clean. No harsh stimulants, no jitters, no weird crash later.

It’s made in a cGMP-certified facility too, so you’re not gambling with your body here. You’re getting a legit, high-quality product. And honestly, whether you’re brand new to the gym or you’ve been grinding for years, this fits. It gives the newbie that first taste of real results and gives the veteran that edge that keeps progress from stalling out.

The confidence boost alone is worth it. When your blood’s moving, your muscles are pumped, and you’re crushing PRs, yeah, it changes how you walk out of that gym. N.O. XT isn’t just a supplement. It’s fuel for that fire that keeps you coming back hungry for more.

Pros

• Contains important ingredients for maximum nitric oxide production.
• Great value for money.
• Long-lasting energy and stamina effects.
• Provides an incredible pump.
• Made by Jacked Factory, one of the best supplement manufacturers in the U.S.

Cons

• Only available on the manufacturer’s website

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#4 Fermented Citrulline

Alright, so you want that feeling where your muscles are so pumped you catch yourself doing a double take in the mirror between sets? This one’s built for exactly that. It’s not dressed up in flashy promises or overloaded with fluff. It’s pure focus, locked in on one job, huge muscle pumps.

At the heart of it is 2 grams of fermented L-Citrulline. That’s it. No filler noise. Just an amino acid that hits your system, converts to L-Arginine, and kicks up your nitric oxide levels in a big way. What does that mean for you? More blood flow, more volume, and yeah, those skin-tight pumps that make the workout feel like it’s doing something real.

And here’s the part I like. It’s clean. No caffeine, no crash, no jittery nonsense that ruins your rhythm. Just a straight-up pump enhancer that works with your body instead of yanking it around with stimulants.

Worried it won’t live up to the hype? Fair enough. But Kaged Muscle backs it with a full-month guarantee. If it doesn’t hit the mark for you, they’ll give you your money back. No stress, no weird hoops to jump through.

Whether you’re already deep in the iron game or just getting started, this could be the little spark your routine needs. It’s simple, it’s powerful, and it delivers where it counts. Give it a run and see how you feel when everything’s firing. You’ll know it when it happens.

Pros:

• No filler ingredients, just fermented L-Citrulline
• Inexpensive
• Not made from duck feathers or human hair like most L-Citrulline products
• Vegetarian friendly
• Made to produce nitric oxide

Cons:

• You can only buy from their website.

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Related: Supplement Stacks That Build the Most Muscle

 

#5 BSN Nitrix 2.0

Next up, we’ve got Nitrix 2.0 by BSN. And yeah, it definitely looks the part. The branding is strong, the name sounds aggressive, and on the surface, the formula checks a few important boxes.

You’re getting 3 grams of L-Citrulline per day, which is a solid start if you’re chasing bigger pumps and better endurance. That’s one of the core ingredients in any decent nitric oxide booster, and it’s here in a respectable dose.

But here’s where things get a little shaky. Instead of keeping the formula focused, they packed it with a ton of extras, hawthorn, grape seed, pomegranate, red pepper, black pepper, and more. Sounds impressive, but in reality? It spreads the formula thin. Sometimes less is more, especially when you’re trying to dial in on blood flow and performance. With Nitrix 2.0, the pump is there… just not as intense or as long-lasting as you’d want.

And then there’s the dosing. Six tablets a day. Not two, not four, six. If you’re cool with that kind of pill commitment, no problem. But for most people, it’s a hassle. No powder option, no easy mix, just a big handful of tablets, every day.

Is it terrible? No. But when you stack it against the top dogs on this list, Nitrix 2.0 feels like it’s trying to do too much without truly excelling at one thing.

If you’re a longtime BSN fan or just want a broader blend that covers more than pumps, give it a shot. But if you’re chasing tunnel-vision focus, sleeve-busting fullness, and real gym-floor performance, there are stronger, cleaner, more efficient options out there.

Pros

• Offers a better absorption rate of amino acids and essential nutrients.
• Contains compounds that support metabolic functions.
• Contains Creatine.
• Provides a decent amount of energy.

Cons

• Too many ingredients lower its potency.
• Creatine and water retention could give you a non-ripped appearance.
• Does not contain Arginine, one of the best ingredients in a nitric oxide booster.

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#6 Cellucor NO3 Chrome

Let’s talk about NO3 Chrome from Cellucor. It’s pitched as a stimulant-free nitric oxide booster that’s all about bigger pumps and better gym performance. Sounds solid on the surface, but let’s dig in.

The formula centers around something they call the NO3 blend, which includes Arginine Nitrate. That’s basically a combo of L-Arginine and Nitrate, both known for increasing blood flow and helping you feel more “swollen” during training. They also include Arginine AKG, L-Citrulline, and Grape Seed Extract. All of those can help, sure, but when you really look at the dosages and synergy… it starts to feel a little underwhelming.

Here’s the deal. Compared to heavy-hitters like NO XT, NO2 Max, or the top dog NitroCut, NO3 Chrome just doesn’t hit as hard. The ingredient list sounds decent, but the impact isn’t quite on the same level. Pumps are there, but they’re not the “leave-the-gym-looking-jacked” kind. More like, “okay I feel a little tighter, maybe” kind.

That said, it’s stimulant-free, which some people will appreciate, especially if you train late or don’t want to mess with caffeine. It’s also easy to stack with a pre-workout that already has stimulants baked in.

Bottom line? NO3 Chrome is fine if you’re looking for something simple, non-stim, and stackable. But if you’re chasing serious performance, sleeve-stretching pumps, and noticeable blood flow from the first few sets, you’ve got stronger options sitting higher on the list. Not a bad product, just not the one you reach for if you’re going all in.

Pros

• Citrulline Malate is one of the best forms of L-Citrulline.
• This natural nitric oxide supplement has  less risk of side effects.
• Can be used in a performance-enhancing stack.
• Gives a reasonable amount of energy and stamina.

Cons

• Too expensive to be used long term.
• Dosage is quite high for it to take effect.
• Secret proprietary formula means you’re likely getting lower dosages of the important ingredients.

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Related: The 10 Best Supplements to Make Your Veins Pop

 

#7 NO2 Max by CrazyBulk

Let’s talk about NO2 Max by CrazyBulk. These guys have been around the block, and they know what lifters actually want from a nitric oxide supplement. No fluff, no gimmicks, just something that hits hard and helps you perform better.

This formula is all-natural, but don’t let that fool you. The ingredients are backed by science and handpicked to ramp up nitric oxide production. The result? More blood flow, stronger pumps, better endurance, and faster recovery. Whether you’re looking to bulk, lean out, or just bring more intensity to every workout, this one helps you show up ready.

One of the things that makes NO2 Max stand out is how stackable it is. You can run it solo, or you can layer it with other CrazyBulk supplements and take things to another level. It’s designed to play well with others, which is a big plus if you’re already deep into your supplement stack.

Recovery’s another strong point. You’ll feel like you can bounce back quicker and get after it again without dragging. That matters when you’re training hard and trying to stay consistent.

You might start noticing results in just a few weeks, maybe sooner if your diet and training are locked in. It’s not hype, it’s just a formula that works when you do.

If you’re serious about making progress and want something that delivers without the sketchy ingredients or empty promises, NO2 Max is worth a shot. It’s simple, effective, and built to help you push past whatever’s holding you back.

Pros

• Get steroid-like effects without the actual steroids.
• One of the best nitric oxide boosters that work very well.
• Get an awesome pump and greater endurance.
• NO2 Max can be stacked with other muscle-boosting supplements.

Cons

• Growing muscle still requires hard work and dedication from you.

 

How We Decided

There is a plethora of nitric oxide supplements available, many of which can make outlandish claims about their effectiveness. Here’s how we selected products that actually work.

Ingredients

Navigating the maze of nitric oxide supplements can be overwhelming. With so many options and bold promises, it’s hard to know what actually works. So, here’s how I broke it down to find the best nitric oxide supplements that might be just the right fit for you.

L-arginine vs. L-citrulline Arginine and citrulline are like siblings in the world of amino acids. Both aim to help your body create more nitric oxide, that sought-after “pump” you crave in the gym. But, just like siblings, they each have their own personalities. While the jury is still out on which one is the star performer, some research hints that citrulline might edge out arginine. You’ll find both in the options I’ve selected, so you can choose the one that vibes best with you.

Beetroot Now here’s a humble vegetable making a big splash. Beetroot’s rich in dietary nitrate, something that can boost your nitric oxide levels, even possibly giving your athletic performance a lift. But here’s a fun twist – it might depend on your fitness level. Some folks might find beetroot’s effects more noticeable than others. If you like to keep things natural, beetroot could be a great choice for you.

Dosage Imagine walking a tightrope; that’s kind of what finding the right dosage is like. Too little, and you won’t feel a thing. Too much, and well, that’s not ideal either. I’ve chosen supplements that aim for that “just right” spot, but it’s smart to have a chat with your doctor to find the perfect balance for you.

Ingredients Ah, the great puzzle of reading a supplement label. What’s necessary, and what’s just noise? Believe me, I’ve scrutinized these products to make sure that if something’s in there, it’s serving a purpose. Whether it’s a little caffeine kick or something more, you won’t find any unnecessary frills here.

What’s the takeaway? It’s your body, and you know it best. With the array of options out there, I’ve aimed to highlight the nitric oxide supplements that stand out in quality, effectiveness, and integrity. Whether you’re drawn to amino acids, enchanted by beetroot, or looking for that well-rounded dose, there’s something here for you.

And remember, the supplement world can be a bit wild, so don’t hesitate to reach out to a healthcare professional who can help you navigate it with confidence. Because at the end of the day, it’s not just about finding the right product; it’s about finding the right product for you.

 

What Is Nitric Oxide Supplementation?

So, nitric oxide, often just called NO, is a naturally occurring molecule in your body. It gets made when an enzyme breaks down arginine, an amino acid your body already uses for a bunch of important stuff. When NO is released, it tells your blood vessels to relax and expand. That means more blood flow, more oxygen, and more nutrients going exactly where they need to go, especially during training.

That increased blood flow? It’s a game-changer. Better muscle pumps. Faster recovery. More endurance. Not to mention it helps you feel like your body’s actually doing something in the gym, not just dragging through another session.

The best nitric oxide supplements work by boosting your body’s ability to make more of this stuff. They usually include ingredients like citrulline, arginine, glutathione, and beta-alanine. Citrulline and arginine in particular are your heavy hitters. These amino acids act as precursors, they give your body the raw materials it needs to make more nitric oxide and get things flowing.

Bottom line? More nitric oxide means better workouts. If you want to lift heavier, recover faster, and leave the gym with your veins trying to punch through your skin, nitric oxide is something worth paying attention to. It’s not hype, it’s biology, just dialed up for people who actually train hard.

 

Best Nitric Oxide Boosting Ingredients

Arginine

Arginine, also known as L-Arginine, earns its spot in nearly every serious nitric oxide supplement for good reason. This amino acid is one of your body’s go-to raw materials for making nitric oxide,  the molecule that opens up blood vessels, improves circulation, and helps your muscles get more of what they need during training.

But that’s just the start. Arginine also boosts HGH, or human growth hormone, which plays a major role in muscle growth, fat loss, and recovery. The more HGH you’ve got flowing, the faster you bounce back from brutal workouts, the more testosterone your body can potentially produce, and the easier it gets to pack on lean mass.

There’s also real science behind it. Research suggests Arginine may help with everything from lowering blood pressure to improving endurance. And yeah, it even shows promise in the bedroom. By relaxing certain blood vessels, it may help with erectile function too. So whether you’re chasing gains, trying to lean out, or just want better performance all around, Arginine brings a lot to the table.

 

Citrulline

Citrulline doesn’t get as much hype as some other ingredients, but it’s quietly one of the most important pieces in any nitric oxide stack. On its own, it’s solid. But paired with Arginine? That’s where it starts punching way above its weight.

The two work in tandem. You take Citrulline, your body converts it into Arginine, and that gets the nitric oxide production really going. More nitric oxide means better blood flow, fuller muscle pumps, and nutrients getting delivered exactly where they need to go, fast.

But here’s the kicker. It’s not just about the pump. Citrulline in decent doses has been shown to reduce soreness, boost stamina, and help you stay locked in longer during intense sessions. It even helps your body kick out more HGH after a tough lift, which matters if you’re chasing growth.

And yeah, there’s even evidence it helps with ED and cardiovascular performance. Real talk, it’s one of those ingredients that covers more bases than you expect going in.

Citrulline isn’t just a sidekick. It’s a main character in your supplement stack. You want real results, you keep this one in the mix.

 

Beta-Alanine

Beta-Alanine’s been around the block, and if you’ve felt that signature tingle during a workout, you’ve met it already. But this amino acid is more than just a buzz, it helps fight the acid buildup that wrecks your endurance mid-set.

By buffering that acid, Beta-Alanine keeps your muscles firing longer and harder, especially during high-intensity training. You’ll notice less burnout, more reps, and over time, better gains.

It’s not flashy. It just works. If you’re serious about training longer and recovering faster, this is one of those ingredients that earns its spot in your stack.

 

Glutathione

Glutathione doesn’t get the spotlight it deserves, but it should. It’s built from three key amino acids, cysteine, glycine, and glutamine, and acts as your body’s frontline antioxidant. Think of it as your cellular cleanup crew, keeping your immune system sharp and your liver humming.

Training hard? Chasing serious gains? You’re burning through your Glutathione reserves faster than you think. And when it runs low, recovery slows, aging speeds up, and muscle-building takes a hit.

Keeping your Glutathione levels high helps you stay in peak form, recover quicker, and even shift stored fat into lean muscle. It’s not just a health thing. It’s a performance thing.

 

Benefits of Nitric Oxide Supplements

Massive Boost In Muscle Performance

Nitric oxide supplements are your go-to if you’re chasing that extra edge in the gym. Not the kind of edge that just gets you sweating harder, but the kind that makes your veins pop, your endurance spike, and your strength feel bottomless.

Here’s what’s happening behind the scenes. When nitric oxide kicks in, it opens up your blood vessels. That means more blood, more oxygen, and more nutrients rushing to your muscles while you’re training. It’s like flipping a switch from regular to beast mode.

Suddenly, you’re not just lifting. You’re moving weight that used to bury you. That ache you usually feel when lactic acid builds up? It’s dulled. You last longer, push harder, and recover quicker. And yeah, that full, skin-tight muscle pump? It’s not just for looks. More blood flow equals more growth potential.

It’s not magic, but it sure feels like it when you’re halfway through a brutal workout and still charging like you just started. That’s what nitric oxide does when it’s working right.

Quicker Recovery Time

Citrulline’s one of those ingredients that sneaks up on you, in the best way possible. You’re not just popping some fancy amino acid. You’re unlocking faster recovery, cleaner muscle function, and a better shot at getting back in the gym without feeling wrecked.

When you train hard, your muscles take a beating. Waste products like ammonia and lactic acid start piling up, and that’s what drags you down. Citrulline malate steps in, clears the mess out, and cranks up blood flow so your muscles get what they need and bounce back faster.

Less soreness, less downtime. Which means you’re not just thinking about your next session, you’re already planning it. The more consistently you can train, the more chances you’ve got to build real muscle and finally start seeing that lean, athletic build you’ve been after. Simple as that.

 

Treats Erectile Dysfunction

Erectile dysfunction is a condition where one fails to achieve a satisfactory erection for sexual purposes.

Individuals who are suffering from the effects of ED may find help in the form of Nitric Oxide supplements. Though most of these NO products are marketed towards bodybuilders, gym goers and athletes, there’s no stopping ED patients from trying it out to achieve sexual satisfaction.

As you may know, nitric oxide widens the blood vessels, allowing more blood to flow to the muscles and other extremities, including the penis. The mechanism of action allows the chambers found inside the penis to fill with blood and get rock hard results. Men who want to satisfy their partners can take the pill and get their manhood up for maximum performance in the bedroom.

 

How Much Go Nitric Oxide Supplements Cost?

Nitric oxide supplements won’t break the bank, but prices still vary depending on what you’re getting. Some are basic, just citrulline or arginine. Others pack in extra ingredients, act more like a full pre-workout, and cost a bit more.

Here’s the real thing to pay attention to: cost per serving. Not the full bottle price. Most land somewhere between a buck and two bucks per scoop or dose. A few go higher, especially the loaded ones, but even then you’re not dropping anything crazy.

If you’re on a budget, there are plenty of stripped-down options that still get the job done. If you’re willing to spend a little more, you’ll find some formulas that go above and beyond. Either way, you’ve got choices that won’t wreck your wallet. Just pick the one that fits your goals.

 

Considerations Before Buying A Nitric Oxide Supplement

 

Conclusion

Nitric oxide supplements aren’t like your typical pre-workouts. They don’t load you up with caffeine or flashy buzzwords. Instead, they quietly go to work under the hood—helping your body produce more nitric oxide so blood flows better, pumps hit harder, and you last longer in the gym.

Some rely on citrulline, others lean on arginine, and a few throw in beetroot for good measure. There’s no one-size-fits-all, but the right formula can make a real difference when you’re chasing strength, size, or just an edge.

You’ve got options now. Pick the one that fits your style, your goals, and your grind. Then get after it.

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